Jennifer Guerriero, PhD
Dr. Guerriero's publications
Dr. Guerriero received her bachelor’s degree in BioChemistry from Northeastern University and has a PhD in Molecular and Cellular Biology and Immunology and Pathology from Stony Brook University where she trained under Dr. Wei-Xing Zong and completed her thesis entitled, “A study of cell death pathways and innate immunity in cancer chemotherapy”.
Dr. Guerriero completed her postdoctoral training in the laboratory of Dr. Anthony Letai at Dana-Farber Cancer Institute where she investigated the role of tumor associated macrophages in breast cancer and identified novel mechanisms to target pro-tumor macrophages to an anti-tumor phenotype to induce tumor regression. She built "Team Macrophage" during her postdoctoral fellowship, including Dr. Anita Mehta and Emily Cheney, who are now part of the Breast Tumor Immunology Laboratory.
Dr. Guerriero transitioned to a faculty position as an Instructor in Medicine at Harvard Medical School and joined Dr. Mittendorf's laboratory as the Director of the Breast Tumor Immunology Laboratory in the Susan F. Smith Women’s Cancer Program at Dana-Farber Cancer Institute.
In October 2020 Dr. Guerriero launched her independent laboratory at Brigham and Women's Hospital and continues to serve as the Director of the Breast Tumor Immunology Laboratory.
Her research interests include harnessing the anti-tumor potential of tumor-associated macrophages for cancer immunotherapy in triple negative breast cancers, understanding how tumor cell intrinsic mutations regulate the tumor microenvironment and understanding the biology, phenotype and ontogeny of tumor macrophages.
Interests Outside of Lab
Apart from research Dr. Guerriero likes to spend time with her husband (Jason) and three children, Gabriella (9), Michael (6) and John (3), attend Jason's hockey games (Go Brown!), run and read.